Short answerYes. In people who play sport, ankle supports roughly halved the number of ankle sprains, and the gain was greater in those who had sprained an ankle before.
Evidence grade
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Good evidence it helps
What it is
An ankle brace is a support worn around the ankle to limit the sideways rolling that causes most sprains. The trials used semi-rigid braces and air-cast braces, and some used tape. This page covers prevention in active people, not treatment of a new sprain.
What the research shows
pooled trials of people in active sports such as soccer and basketball. External ankle supports reduced the number of ankle sprains by almost half (relative risk 0.53, range 0.40 to 0.69). The reduction was greater in people who had sprained an ankle before, and it was still seen in those who had not. Supports did not change the severity of sprains that happened, or the number of other leg injuries.
The review searched for trials only up to the year 2000. found that taping, bracing and balance training were each effective in preventing repeat sprains. A brace or tape combined with balance training gave the best results for the least burden on the athlete.
Risks and effort
Braces are bulky in a shoe, and they have to be worn for every session to protect you.