Cochrane review1Therapeutic ultrasound for knee and hip arthritis
Who and when. A Cochrane team at the University of Bern, Switzerland, published January 2010.
What they did. They searched for randomised trials comparing ultrasound treatment with a sham machine or no treatment. They found five small trials with 341 people, all with knee arthritis and none with hip arthritis.
What they found. Pain was about 1.2 points lower on a 10 point scale with ultrasound. Function may have improved but the result could have been chance. The trials were small, poorly reported and very different from each other. No side effects were seen in the two trials that looked.
What it means. There may be a small benefit, but the evidence is too thin to be sure, which is why the grade is not enough evidence yet. This review has not been updated since 2010.
Rutjes AWS, Nüesch E, Sterchi R, Jüni P. Therapeutic ultrasound for osteoarthritis of the knee or hip. Cochrane Database Syst Rev. 2010;(1):CD003132.
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Systematic review2How much of the effect is placebo?
Who and when. Researchers at Brigham and Women’s Hospital and Harvard, published in Osteoarthritis and Cartilage in 2020.
What they did. They took 25 randomised trials of acupuncture, ultrasound, laser and TENS for knee arthritis and worked out what share of the pain relief in the treated group was also seen in the sham group.
What they found. For ultrasound, laser and TENS together, about 69 percent of the pain relief was also seen with the sham treatment. For acupuncture it was 61 percent.
What it means. Most of the relief people feel from machine treatments like ultrasound comes from the attention, the visit and the expectation, not the sound waves.
Chen AT, Shrestha S, Collins JE, Sullivan JK, Losina E, Katz JN. Estimating contextual effect in nonpharmacological therapies for pain in knee osteoarthritis. A systematic analytic review. Osteoarthritis Cartilage. 2020;28(9):1154-1169.
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Australian guideline3RACGP guideline for knee and hip osteoarthritis
Who and when. The Royal Australian College of General Practitioners, with Australian arthritis researchers, second edition 2018. This is the guideline Australian GPs follow.
What they did. An expert panel reviewed the research on each treatment and graded how strongly to recommend it, for or against.
What they found. Therapeutic ultrasound is conditionally recommended against for knee and hip arthritis.
What it means. Australian GPs are advised not to suggest it.
Royal Australian College of General Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd ed. East Melbourne: RACGP; 2018.
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US guideline4American College of Rheumatology guideline for osteoarthritis
Who and when. The American College of Rheumatology and the Arthritis Foundation, published January 2020. The panel included patients as well as doctors and therapists.
What they did. A literature review team summarised the benefits and harms of every common treatment, and a voting panel graded each recommendation as strong or conditional.
What they found. The panel made a conditional recommendation against pulsed ultrasound for knee arthritis, because the trials were small and of low quality.
What it means. Not recommended, but with less certainty than for some other treatments.
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis Rheumatol. 2020;72(2):220-233.
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International guideline5OARSI guideline for non-surgical treatment of knee and hip osteoarthritis
Who and when. The Osteoarthritis Research Society International, the main scientific body for arthritis research, published July 2019.
What they did. A panel of 21 experts from 11 countries reviewed the pooled trial evidence for 60 different treatments and voted on each one.
What they found. Ultrasound was not recommended for knee or hip arthritis at any level.
What it means. The international panel found no case for it.
Bannuru RR, Osani MC, Vaysbrot EE, Arden NK, Bennell K, Bierma-Zeinstra SMA, Kraus VB, Lohmander LS, Abbott JH, Bhandari M, Blanco FJ, Espinosa R, Haugen IK, Lin J, Mandl LA, Moilanen E, Nakamura N, Snyder-Mackler L, Trojian T, Underwood M, McAlindon TE. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage. 2019;27(11):1578-1589.
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